产品货号：
GS4608
中文名称：
重组小鼠TARC/CCL17
英文名称：
Recombinant Murine Thymus and Activation Regulated Chemokine/CCL17
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 7.9kDa,a single non-glycosylated polypeptide chain containing 70 amino acids.
储存条件：冷冻（-20℃）
概述
Murine CCL17 also known as TARC,Small-inducible cytokine A17,Thymus and activation-regulated chemokine and SCYA17,is encoded by the CCL17 gene located on the chromosome 8.Among CC chemokine family members,CCL17 has approximately 24 – 29%amino acid sequence identity with RANTES,MIP-1α,MIP-1β,MCP-1,MCP-2,MCP-3 and I-309.CCL17 is a secreted protein and expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently.It signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes.CCL17 play an important role in skin diseases such as atopic dermatitis,bullous pemphigoid and mycosis fungoides.Recombinant CCL17 has been shown to be chemotactic for T cell lines but not monocytes or neutrophils.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠TARC/CCL17，TARC/CCL17, Murine
储存条件：冷冻（-20℃）
概述
Murine CCL17 also known as TARC,Small-inducible cytokine A17,Thymus and activation-regulated chemokine and SCYA17,is encoded by the CCL17 gene located on the chromosome 8.Among CC chemokine family members,CCL17 has approximately 24 – 29%amino acid sequence identity with RANTES,MIP-1α,MIP-1β,MCP-1,MCP-2,MCP-3 and I-309.CCL17 is a secreted protein and expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently.It signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes.CCL17 play an important role in skin diseases such as atopic dermatitis,bullous pemphigoid and mycosis fungoides.Recombinant CCL17 has been shown to be chemotactic for T cell lines but not monocytes or neutrophils.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rMuTARC/CCL17 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | ARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP |
相关搜索：重组小鼠TARC/CCL17，TARC/CCL17, Murine